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Nobel Prize
In this image, the proteasome—a cell’s protein disposal system—is shown in tan and grey. A protein called midnolin (in red) connects with two key parts of the proteasome, RPN1 (blue) and RPN11 (green), to help deliver damaged or unwanted proteins for breakdown. This interaction helps keep cells healthy by clearing out the cellular junk. [Image: UTSW]
UT Southwestern Maps a Cancer-Enabling Protein That Lets B-Cell Tumors Hang On—With a Nobel Laureate on the Case
by Lance Murray | Jun 16, 2025
The protein—implicated in blood cancers like leukemia, lymphoma, and multiple myeloma—was decoded in near-atomic detail by UT Southwestern researchers, including Nobel Prize winner Bruce Beutler. In lab models, turning off midnolin wiped out up to 92% of cancer cells—with minimal impact on healthy ones, according to UT Southwestern.
by David Seeley |
Aug 6, 2024
A study co-led by UTSW's Jin Huk Choi, Ph.D., and Nobel Prize winner Bruce Beutler, M.D., found that targeting a gene-produced protein called ZFP574 "reduced the amount of malignant B cells by as much as 92%." Their findings could lead to new treatments for leukemias and lymphomas—and potentially other cancers, too.
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by Alex Edwards |
Dec 8, 2021
The deal combines Materia’s Nobel Prize-winning hydrocarbon-based materials technology with ExxonMobil’s manufacturing capabilities to commercialize a new class of structural materials. Applications could include everything from wind power turbine blades to EV parts to sustainable construction products.
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by Patrick Kobler |
Jan 27, 2016
The God Particle, which is crucial to our understanding of the universe, was discovered in part by researchers at the University of Texas at Arlington.
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Photo courtesy of University of North Texas
Education: State of Innovation in Dallas-Fort Worth
by Patrick Kobler | Dec 15, 2015
Dallas Fort-Worth has committed to approaching its educational landscape with a focus on the 21st century.
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![Erica Kosemund, Chief Brand Officer, Choctaw Nation of Oklahoma; Gillian Breidenbach, Chief Partnership Officer, North Texas FWC Organizing Committee; Chief Gary Batton, Chief of Choctaw Nation of Oklahoma; Monica Paul, Executive Director of Dallas Sports Commission and President of North Texas FWC Organizing Committee; John Hobbs, Senior Executive Officer of Communications, Choctaw Nation of Oklahoma; and Heidi Grant, Senior Executive Officer of Commerce Administration, Choctaw Nation of Oklahoma, celebrate Choctaw Casinos & Resorts becoming an Official Dallas World Cup 2026 Host City Supporter. [Photo: North Texas FWC Organizing Committee/Choctaw Casinos & Resorts]](https://s24806.pcdn.co/wp-content/uploads/2025/12/FIFA-Choctaw-dec-2025.jpg)
