KRAS

lung cancer

UTSW Researchers Make Lung Cancer Breakthrough

by | Oct 4, 2016

Researchers at UT Southwestern Medical Center said they have discovered what they called a vulnerability in the armor of a so-called “undruggable” lung cancer, and they have found an existing drug they said may provide a treatment.

In a release, UT Southwestern said the researchers were working in four separate labs when they found that the drug Selinexor (KPT-330) killed lung cancer cells and shrank tumors in mice when used against cancers driven by the KRAS cancer gene, one that is aggressive and difficult to treat....

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