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Bruce Beutler
Researchers found that deleting or degrading a protein called ZFP574 eliminates leukemic B cells (blue) over nonmalignant B cells in vivo. [Photo: UTSW]
UT Southwestern Researchers Target a Protein To Fight Leukemia, Lymphoma
by David Seeley | Aug 6, 2024
A study co-led by UTSW's Jin Huk Choi, Ph.D., and Nobel Prize winner Bruce Beutler, M.D., found that targeting a gene-produced protein called ZFP574 "reduced the amount of malignant B cells by as much as 92%." Their findings could lead to new treatments for leukemias and lymphomas—and potentially other cancers, too.
