MORE►
Bruce Beutler
This fluorescent microscopy image shows GPR45 (green) localized in the primary cilia (blue), where it facilitates the transport of Gαs (red) into the cilia of hypothalamic cells. [Image: UTSW]
Appetite-Regulating Gene Discovery at UTSW Could Lead to Future Obesity Therapies
by Lance Murray | Jul 24, 2025
Using a new tool developed at UT Southwestern Medical Center, researchers identified a gene that seems to be key in regulating food intake, offering a different pathway for potential obesity treatments.
by Lance Murray |
Jun 16, 2025
The protein—implicated in blood cancers like leukemia, lymphoma, and multiple myeloma—was decoded in near-atomic detail by UT Southwestern researchers, including Nobel Prize winner Bruce Beutler. In lab models, turning off midnolin wiped out up to 92% of cancer cells—with minimal impact on healthy ones, according to UT Southwestern.
MORE►
by David Seeley |
Aug 6, 2024
A study co-led by UTSW's Jin Huk Choi, Ph.D., and Nobel Prize winner Bruce Beutler, M.D., found that targeting a gene-produced protein called ZFP574 "reduced the amount of malignant B cells by as much as 92%." Their findings could lead to new treatments for leukemias and lymphomas—and potentially other cancers, too.
MORE►
