Bruce Beutler

French Researcher Joining UTSW Is Among Recipients of Up to $25M Cancer Grand Challenges Award

by | Mar 11, 2026
The Cancer Grand Challenges initiative, co-founded in 2020 by the National Cancer Institute and Cancer Research UK, provides funding over approximately five years to interdisciplinary teams addressing some of the most complex research questions surrounding cancer.
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Appetite-Regulating Gene Discovery at UTSW Could Lead to Future Obesity Therapies
by | Jul 24, 2025
Using a new tool developed at UT Southwestern Medical Center, researchers identified a gene that seems to be key in regulating food intake, offering a different pathway for potential obesity treatments.
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UT Southwestern Maps a Cancer-Enabling Protein That Lets B-Cell Tumors Hang On—With a Nobel Laureate on the Case
by | Jun 16, 2025
The protein—implicated in blood cancers like leukemia, lymphoma, and multiple myeloma—was decoded in near-atomic detail by UT Southwestern researchers, including Nobel Prize winner Bruce Beutler. In lab models, turning off midnolin wiped out up to 92% of cancer cells—with minimal impact on healthy ones, according to UT Southwestern.
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UT Southwestern Researchers Target a Protein To Fight Leukemia, Lymphoma
by | Aug 6, 2024
A study co-led by UTSW's Jin Huk Choi, Ph.D., and Nobel Prize winner Bruce Beutler, M.D., found that targeting a gene-produced protein called ZFP574 "reduced the amount of malignant B cells by as much as 92%." Their findings could lead to new treatments for leukemias and lymphomas—and potentially other cancers, too.
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