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UT Southwestern
In this image, the proteasome—a cell’s protein disposal system—is shown in tan and grey. A protein called midnolin (in red) connects with two key parts of the proteasome, RPN1 (blue) and RPN11 (green), to help deliver damaged or unwanted proteins for breakdown. This interaction helps keep cells healthy by clearing out the cellular junk. [Image: UTSW]
UT Southwestern Maps a Cancer-Enabling Protein That Lets B-Cell Tumors Hang On—With a Nobel Laureate on the Case
by Lance Murray | Jun 16, 2025
The protein—implicated in blood cancers like leukemia, lymphoma, and multiple myeloma—was decoded in near-atomic detail by UT Southwestern researchers, including Nobel Prize winner Bruce Beutler. In lab models, turning off midnolin wiped out up to 92% of cancer cells—with minimal impact on healthy ones, according to UT Southwestern.
by Lance Murray |
Mar 26, 2025
Boston-based Suffolk said Evan McKee will draw on his proven track record to focus on expanding the company's portfolio across commercial, higher education, institutional, and healthcare projects.
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by Nicole Ward, DRC Data Journalist |
Aug 1, 2024
OncoNano's innovative approach to cancer treatment leverages nanotechnology to bring tumors into the light.
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by Lance Murray |
Mar 11, 2024
Researchers at UT Southwestern Medical Center in Dallas have developed an artificial intelligence (AI) method that writes its own algorithms and may one day operate as an “automated scientist” to extract meaning from complex datasets....
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[Image: Jatuporn Tansirimas/istockphoto]
The Last Word: How To Tackle Mental Health Issues Impacting Texas Youth
by Dallas Innovates | Staff Report | Jun 13, 2023
Concern has swept the nation since COVID hit about the pandemic's lasting affects on the mental health of children and adolescents. But that mental health crisis has actually been worsening for years, even before the pandemic. The Dallas Morning News' Marin Wolf explores what Children’s Health, UT Southwestern, Cook Children's, and Meadows Mental Health Policy Institute are doing to get ahead of the problem.
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by David Seeley |
Apr 17, 2023
Subtle changes in the way people speak could help doctors diagnose cognitive impairment and Alzheimer’s disease—even before symptoms begin to show. That's according to a new study led UT Southwestern researcher Ihab Hajjar, M.D., working with a research team at Emory University in Atlanta. After being given standard cognitive assessments, 206 participants were asked to talk about an art work. Here's what happened next.
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by Dallas Innovates | Staff Report |
Feb 17, 2023
The Cancer Prevention and Research Institute of Texas approved over $90 million in new cancer research and prevention grants at its quarterly meeting near the Texas Capitol on Wednesday—and $20.6 million of that money is coming to North Texas to advance everything from breast cancer and lung cancer screening to "deep learning models" to facilitate T-cell receptor therapies.
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by Lance Murray |
Feb 13, 2023
The new two-story lab and office building will offer "the first institutional-quality space" in the DFW market, according to marketing materials.
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UT Southwestern executives Holly Crawford, EVP for business affairs, and Jeremy Falke, vice president and chief human resources officer [Photos: UT Southwestern]
How UT Southwestern Medical Center Nurtures Next-Gen Health Care Leaders
by Quincy Preston | Dec 30, 2022
As one of the nation’s premier academic medical centers, nurturing employees for management and leadership roles is mission critical. The medical center, with its workforce of nearly 23,000, received the 2022 BOLD award for its leadership development.
“As we do with our scientific, medical, and training missions, we apply data-driven strategies to nurture leaders who contribute to our institution’s culture of integrity, inclusiveness, and collaboration, and extend those qualities throughout the organization,” Holly Crawford said.
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by David Seeley |
Dec 20, 2022
The early-stage startup's QmTRIAGE software platform uses AI and machine learning to detect early breast cancers with a "high rate" of accuracy, MedCognetics says. The company has worked with UT Southwestern and UT Dallas to ensure its AI improves outcomes for "all ethnicities," at a time when racial disparities in AI have become a growing concern.
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by Kevin Cummings |
Oct 24, 2022
The Biotech+ Hub at Pegasus Park in Dallas has been attracting more and more life science startups and university teams. Now a whole herd of Mustangs are about to stampede there. The SMU Institute for Computational Biosciences at Pegasus Park will have space at the 23-acre development. SMU researchers from a variety of disciplines will be focusing on bio-scientific discoveries, leveraging advanced computational algorithms and technologies.
"We're excited to give SMU faculty this new opportunity to pursue world-changing research for good and to do so in close proximity to a broad range of academic, medical, corporate, and non-profit collaborators," says SMU Provost Elizabeth Loboa. "We're excited to give SMU faculty this new opportunity to pursue world-changing research for good and to do so in close proximity to a broad range of academic, medical, corporate, and non-profit collaborators," says SMU Provost Elizabeth Loboa.
"We're excited to give SMU faculty this new opportunity to pursue world-changing research for good and to do so in close proximity to a broad range of academic, medical, corporate, and non-profit collaborators," says SMU Provost Elizabeth Loboa. "We're excited to give SMU faculty this new opportunity to pursue world-changing research for good and to do so in close proximity to a broad range of academic, medical, corporate, and non-profit collaborators," says SMU Provost Elizabeth Loboa.
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by Lance Murray |
Sep 28, 2022
Over 150 scientists across dozens of departments will be part of the elite National Institutes of Health-funded, university-wide interdisciplinary research center. Dallas' UT Southwestern Medical Center is the only institution in Texas to be selected for the NIH initiative.
UTSW wants to translate scientific discoveries into new therapeutic strategies for the prevention and treatment of obesity, which it describes as a chronic disease affecting more than 40% of the U.S. population, with medical costs nearing $175 billion.
UTSW wants to translate scientific discoveries into new therapeutic strategies for the prevention and treatment of obesity, which it describes as a chronic disease affecting more than 40% of the U.S. population, with medical costs nearing $175 billion.
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Illustration: elenabs/iStock
CPRIT Is Funding the Development of Products That Fight Cancer
by Kevin Cummings | Sep 6, 2022
The Cancer Prevention & Research Institute of Texas has provided more than $3.1 billion in funding toward the development of cancer-fighting therapeutics, devices, diagnostics, and tools since 2010. It's now issued a call for startups and early-stage companies to apply for product development research grants for the 2023 fiscal year.
“CPRIT’s mission is to invest in the research prowess of Texas institutions while expediting breakthroughs in cancer cures and prevention,” CEO Wayne Roberts said last May.
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by Kevin Cummings |
Aug 29, 2022
UT Southwestern Medical Center at RedBird is a new, 150,000-square-foot hospital that instantly becomes a core feature of the redeveloped Redbird Mall. Located in a former Sears store, the new hospital marks the first time UTSW has transformed a former retail space into a regional medical center.
“In RedBird, we recognized an opportunity to expand our footprint in Dallas and to have a vital presence in a community that has traditionally been underserved by the health care industry," said UTSW's Dr. Marc Nivet.
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by Kevin Cummings |
Jul 25, 2022
Plus, Fort Worth's Harvest Returns raises new fund; new Ryan acquisition makes 2022 its most active M&A year; OpTic Gaming acquires Dallas chatbot startup; Dallas legal education firm boosts digital content library; and Fort Worth's Novaria Group acquires firm with giant aerospace clients.
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by Kevin Cummings |
Jul 20, 2022
UT Dallas-based Qualia Oto is developing the next generation of cochlear implants, and has announced closing a Series A preferred round of around $1.64 million.
Unlike typical cochlear implants that use bundles of wires attached to a receiver to stimulate the auditory nerve, Qualia Oto’s implant uses thin-film electrode arrays embedded in a polymer, allowing for more contact with the inner ear. That translates to a higher quality and range of sounds that are able to be transmitted.
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