In this image, the proteasome—a cell’s protein disposal system—is shown in tan and grey. A protein called midnolin (in red) connects with two key parts of the proteasome, RPN1 (blue) and RPN11 (green), to help deliver damaged or unwanted proteins for breakdown. This interaction helps keep cells healthy by clearing out the cellular junk. [Image: UTSW]
A clinical trial led by researchers at UT Southwestern Medical Center in Dallas could help bring an experimental treatment for depression closer to approval from the U.S....
The 2024 DocStars: Anezi Uzendu, M.D., F.A.C.C.; Sarah Lieber, M.D., M.S.C.R.; Ethan Sanford, M.D. [Photo: Ren Morrison]
Researchers at UT Southwestern Medical Center in Dallas have identified a compound that selectively eliminates cancer cells while sparing immune cells in a form of cell death known as ferroptosis, according to a news release.
UTSW said the findings, published in Science Translational Medicine earlier this year, could lead to new treatments for a wide variety of cancer types....
Basak Dogan, M.D., is Professor of Radiology, Director of Breast Imaging Research, and member of the Harold C. Simmons Comprehensive Cancer Center at UT Southwestern. [Photo: UT Southwestern]