Researchers at UT Southwestern Medical Center said they have discovered what they called a vulnerability in the armor of a so-called “undruggable” lung cancer, and they have found an existing drug they said may provide a treatment.
In a release, UT Southwestern said the researchers were working in four separate labs when they found that the drug Selinexor (KPT-330) killed lung cancer cells and shrank tumors in mice when used against cancers driven by the KRAS cancer gene, one that is aggressive and difficult to treat....